The Black-White Pixels Ratio in Medial Temporal Lobe Brain Structure in Transcranial B-Images as a Measurable Marker of Alzheimer's Disease Probability: The Reproducibility Overview

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F47813059%3A19240%2F20%3AA0000675" target="_blank" >RIV/47813059:19240/20:A0000675 - isvavai.cz</a>

Alternative codes found

RIV/26867184:_____/20:N0000023

Result on the web

<a href="https://ieeexplore.ieee.org/document/9238214" target="_blank" >https://ieeexplore.ieee.org/document/9238214</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23919/SoftCOM50211.2020.9238214" target="_blank" >10.23919/SoftCOM50211.2020.9238214</a>

Result language

angličtina

Original language name

The Black-White Pixels Ratio in Medial Temporal Lobe Brain Structure in Transcranial B-Images as a Measurable Marker of Alzheimer's Disease Probability: The Reproducibility Overview

Original language description

The objective of the presented study is to introduce analysis the black-white pixels ratio in medial temporal lobe (MTL) brain structure in digitized transcranial B-images using our developed software B-MODE Assist. This ratio could be a significant marker related to the echogenicity grade. In B-image, the MTL is stable anechogenic structure but increased echogenicity of surrounding cortex is detectable in the case of MTL atrophy; the atrophy predicts Alzheimer's Disease. Within this study, a set of 97 B-images is used. There are two key goals of this pilot study; verify the reproducibility of the ratio between two observers and to show that the ratio is not much different in the case of original image in comparison with a magnified segment and using constant brightness increasing; the ratio should be independent on image resolution and brightness. To select medial temporal lobe structure, a 20mm square-shaped Region of Interest is used. The correlation coefficient r=0.69 was achieved between two independent, non-experienced observers. The error does not exceed 28 % between 2 non-experienced observers and does not exceed 12 % between the measurements from the same observer. Also, the variance and the range were computed. Achieved results have been judged by an experienced sonographer. In the future, the ratio could be an effective value to determine the MTL atrophy based on the ratio value and possibility to create a rule-based expert system which should help evaluate probability of Alzheimer's Disease based on the cortex echogenicity grade. In general, this approach could be a reliable way to detect risk of Alzheimer's Disease using neurosonological imaging.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

20206 - Computer hardware and architecture

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

2020 International Conference on Software, Telecommunications and Computer Networks (SoftCOM)

ISBN

9781728175386

ISSN

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e-ISSN

1847-358X

Number of pages

6

Pages from-to

1-6

Publisher name

Institute of Electrical and Electronics Engineers Inc.

Place of publication

Croatia

Event location

Split, Hvar; Croatia

Event date

Jan 1, 2020

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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