Modeling of dynamic perfusion test using a two-scale model of tissue parenchyma with layer-wise decomposition

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43915718" target="_blank" >RIV/49777513:23520/12:43915718 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Modeling of dynamic perfusion test using a two-scale model of tissue parenchyma with layer-wise decomposition
Original language description
We developed a model of homogenized perfusion in the 3-compartment medium constituted by several transversely periodic layers, which enable us to approximate flow through different hierarchies of the porosity. A 3D layered structure can be replaced by afinite number of 2D "homogenized layers" coupled by conditions governing the fluid exchange between them. Each layer is assumed to have a locally periodic structure generated by the reference periodic cell. Using this cell, homogenized coefficients relevant to the macroscopic level can be calculated. However, using generalized coupling conditions for geometrically non-matching layers along their interfaces, this approach allows us to approximate the hierarchical structure of the perfusion tree: in eachlayer the periodic microstructure can be different and can be of different size. Then also more separated channel porosities in each layer can be considered. Using the macroscopic flow response, pressures, related perfusion velocities and
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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