Clinical potential of MICA/MICB genes polymorphisms in HSCT

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F23%3A43970826" target="_blank" >RIV/49777513:23520/23:43970826 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Clinical potential of MICA/MICB genes polymorphisms in HSCT

Original language description

The selection process of the optimal donor for haematopoietic stem cell transplantations (HSCT) should be based on HLA match but, if possible, also include other immunogenetic or non-immunogenic parameters with the potential to influence the outcome of transplantation, such as MICA/MICB. Our study aimed to find polymorphisms in MICA and MICB genes and study their effect in AML patients after HSCT. The whole process, including bioinformatics solution, was prepared to be proposed as a potential solution for future clinical use.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project

<a href="/en/project/NV18-03-00277" target="_blank" >NV18-03-00277: Polymorphisms in the NK cells receptors and their ligands within the Czech population</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů