A preliminary in silico study of flow-mediated thrombosis in medical devices

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F24%3A43972702" target="_blank" >RIV/49777513:23520/24:43972702 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/chapter/10.1007/978-3-031-70251-8_7" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-031-70251-8_7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-70251-8_7" target="_blank" >10.1007/978-3-031-70251-8_7</a>

Result language
angličtina
Original language name
A preliminary in silico study of flow-mediated thrombosis in medical devices
Original language description
Failure of blood-contacting medical devices, such as vascular grafts and stents, is often attributed to thrombosis-related complications. To provide an alternative insight into the often very complex interaction between the forming clot and blood flow, the study introduces a continuum-based computational model based on a two-way coupled modelling approach. The basis of the model is formed by three interconnected submodels, each representing an essential part of the highly dynamic thrombosis process (blood clotting, fibrin polymerisation, and platelet plug formation). For the description of blood flow exposed to a coagulation trigger, a multiscale approach is used to ensure physiologically relevant flow conditions even during an imminent vessel blockage.
Czech name
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Czech description
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Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Advances in Mechanism Design IV - Proceedings of TMM 2024
ISBN
978-3-031-70250-1
ISSN
2211-0984
e-ISSN
2211-0992
Number of pages
10
Pages from-to
66-75
Publisher name
Springer
Place of publication
Cham
Event location
Liberec
Event date
Sep 3, 2024
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
001328769400007

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