Fluorescent carbon nanoparticles in cancer diagnostic and therapy systems
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23640%2F24%3A43975706" target="_blank" >RIV/49777513:23640/24:43975706 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/B9780443135910000176" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/B9780443135910000176</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-443-13591-0.00017-6" target="_blank" >10.1016/B978-0-443-13591-0.00017-6</a>
Alternative languages
Result language
angličtina
Original language name
Fluorescent carbon nanoparticles in cancer diagnostic and therapy systems
Original language description
Fluorescent carbon nanoparticles (FCNPs) have emerged as a promising class of nanomaterials for cancer theranostic, combining diagnostic and therapeutic capabilities into a single platform. These nanoparticles (NPs) possess unique optical properties, including tunable fluorescence emission, excellent photostability, and low cytotoxicity, making them attractive for bioimaging and sensing applications. Additionally, FCNPs can act as nanocarriers for delivering chemotherapeutic drugs, gene therapeutics, or photosensitizers for photodynamic therapy. This typical chapter comprehensively overviews the latest developments using FCNPs for cancer diagnosis and treatment. We discuss the various synthesis methods, surface functionalization strategies, and the mechanisms underlying their fluorescence behavior. The applications of FcnPs in cancer cell imaging, tumor targeting, and drug delivery are highlighted, focusing on their ability to enhance the specificity and efficacy of cancer treatment. Recent advances in developing multifunctional FCNPs for multimodal imaging, combined chemo-photodynamic therapy, and stimuli-responsive drug release have also been explored. Furthermore, the challenges and perspectives associated with the clinical translation of FCNPs-based theranostic systems, including biocompatibility, biodistribution, and clearance considerations were addressed. Overall, this chapter underscores the significant potential of FCNPs as versatile nanoplatforms for integrated cancer diagnosis and therapy, paving the way for personalized and targeted cancer management strategies.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
21001 - Nano-materials (production and properties)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Fluorescent Carbon Nanoparticles: Fundamentals and Applications
ISBN
978-0-443-13591-0
Number of pages of the result
49
Pages from-to
367-415
Number of pages of the book
867
Publisher name
Elsevier
Place of publication
Nizozemí
UT code for WoS chapter
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