Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896021" target="_blank" >RIV/60076658:12110/17:43896021 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/17:00098099
Result on the web
<a href="http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007" target="_blank" >http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.11909/j.issn.1671-5411.2017.09.007" target="_blank" >10.11909/j.issn.1671-5411.2017.09.007</a>
Alternative languages
Result language
angličtina
Original language name
Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center
Original language description
Background Prevalence of atrial fibrillation (AF) increases with age. Radiofrequency catheter ablation (RFCA) is an established treatment option superior to antiarrhythmics (AAs). In this study, we investigated safety and efficacy of RFCA of AF in octogenarians. Methods From our database, we extracted procedural and follow-up data for patients >= 80 years with symptomatic AF undergoing RFCA and compared this population to RFCA patients <= 50 years. All patients underwent pulmonary vein isolation (PVI) supplemented by linear lesions in PVl-nonresponders. Arrhythmia-free survival was assessed using seven day Holter every three months post procedure. All patients completed their 12 months follow-up. Results Fifty patients aged >= 80 years (80.5 +/- 1.6 years) were compared to 259 patients aged <= 50 years (43.5 +/- 5.5 years). The RFCA complication rate did not vary between groups. No differences in procedural characteristics were seen after being analyzed by type of AF. Among patients with paroxysmal AF, 71.4% octogenarian vs. 84.7% young patients was free of any arrhythmia, without AAs, after single procedure. For non-paroxysmal AF, arrhythmia-free survival without AAs, was considerably lower (58.6%) octogenarians vs. 81.2%>younger patients, P = 0.023). If AAs were used, arrhythmia-free survival for paroxysmal AF increased to 90.5%o and 92.1%>in octogenarians and younger patients, respectively; and in non-paroxysmal AF it increased to 79.3%>vs. 88.4%>. Conclusions RFCA is a safe and effective strategy to achieve normal sinus rhythm in a highly selected group of octogenarians. Paroxysmal AF ablation in octogenarians has similar clinical effectiveness as that seen in much younger patients. Non-paroxysmal AF ablation has lower, but still reasonable clinical effectiveness.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Geriatric Cardiology
ISSN
1671-5411
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
9
Country of publishing house
CN - CHINA
Number of pages
7
Pages from-to
575-581
UT code for WoS article
000418531400006
EID of the result in the Scopus database
2-s2.0-85035332806