The Ostrava Region, Czech Republic: impact of air pollution on children´s health

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F17%3A43896760" target="_blank" >RIV/60076658:12110/17:43896760 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/17:43913798

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The Ostrava Region, Czech Republic: impact of air pollution on children´s health

Original language description

Introduction: The Moravian-Silesian Region (MSR) is heavily polluted, especially due to heavy industry and local heating, and concentrations of benzo[a]pyrene (B[a]P) are among the highest in the European Union. Methods: To verify the impact of air pollution on the health of the population in the MSR, the morbidity of children was analysed in three studies which are reviewed: 1) morbidity in children; 2) asthma bronchiale in children; and 3) impact of air pollution on the genome of newborns. Morbidity in children was studied in 10 pediatric districts in Ostrava City. Asthma bronchiale was studied in children from Ostrava-Radvanice and the control district of Prachatice, southern Bohemia, by gene expression profiles. The impact of air pollution on the genome of newborns was studied in the district of Karvina and the control district of Ceske Budejovice. Results: In asthmatic children from Ostrava, increased gene expression corresponded to the non-allergic type of asthma. Concentrations of benzo[a]pyrene in the winter of 2014 were 5.36 ? 3.64 vs. 1.45 ? 1.19 ng/ m3 in CB, P &lt; 0.001 in Karvina. In newborns in the polluted district of Karvina, increased oxidative damage affecting immunodeficiency pathways and the neurotrophin signalling pathway, higher amounts of OH-metabolites of PAHs in urine, as well as increased respiratory morbidity in children up to two years of age were observed. Conclusion: Studies in the Moravian-Silesian Region indicate a significant impact of air pollution on children?s health

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

<a href="/en/project/GA13-13458S" target="_blank" >GA13-13458S: Impact of air pollution to genome of newborns</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Public Health Panorama

ISSN

2412-544X

e-ISSN

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Volume of the periodical

3

Issue of the periodical within the volume

2

Country of publishing house

DK - DENMARK

Number of pages

9

Pages from-to

156-164

UT code for WoS article

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EID of the result in the Scopus database

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