Chemistry and Toxicology of Major Bioactive Substances in Inocybe Mushrooms
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F21%3A43902824" target="_blank" >RIV/60076658:12110/21:43902824 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/21:10425973 RIV/00179906:_____/21:10425973
Result on the web
<a href="http://file:///C:/Users/dvapenik/AppData/Local/Temp/ijms-22-02218-v2.pdf" target="_blank" >http://file:///C:/Users/dvapenik/AppData/Local/Temp/ijms-22-02218-v2.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22042218" target="_blank" >10.3390/ijms22042218</a>
Alternative languages
Result language
angličtina
Original language name
Chemistry and Toxicology of Major Bioactive Substances in Inocybe Mushrooms
Original language description
Mushroom poisoning has always been a threat to human health. There are a large number of reports about ingestion of poisonous mushrooms every year around the world. It attracts the attention of researchers, especially in the aspects of toxin composition, toxic mechanism and toxin application in poisonous mushroom. Inocybe is a large genus of mushrooms and contains toxic substances including muscarine, psilocybin, psilocin, aeruginascin, lectins and baeocystin. In order to prevent and remedy mushroom poisoning, it is significant to clarify the toxic effects and mechanisms of these bioactive substances. In this review article, we summarize the chemistry, most known toxic effects and mechanisms of major toxic substances in Inocybe mushrooms, especially muscarine, psilocybin and psilocin. Their available toxicity data (different species, different administration routes) published formerly are also summarized. In addition, the treatment and medical application of these toxic substances in Inocybe mushrooms are also discussed. We hope that this review will help understanding of the chemistry and toxicology of Inocybe mushrooms as well as the potential clinical application of its bioactive substances to benefit human beings.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30108 - Toxicology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1422-0067
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
4
Country of publishing house
CH - SWITZERLAND
Number of pages
13
Pages from-to
2218
UT code for WoS article
000623890600001
EID of the result in the Scopus database
2-s2.0-85101356269