Chemistry and toxicology of major bioactive substances in inocybe mushrooms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50017904" target="_blank" >RIV/62690094:18470/21:50017904 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1422-0067/22/4/2218" target="_blank" >https://www.mdpi.com/1422-0067/22/4/2218</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ijms22042218" target="_blank" >10.3390/ijms22042218</a>

Result language

angličtina

Original language name

Chemistry and toxicology of major bioactive substances in inocybe mushrooms

Original language description

Mushroom poisoning has always been a threat to human health. There are a large number of reports about ingestion of poisonous mushrooms every year around the world. It attracts the attention of researchers, especially in the aspects of toxin composition, toxic mechanism and toxin application in poisonous mushroom. Inocybe is a large genus of mushrooms and contains toxic substances including muscarine, psilocybin, psilocin, aeruginascin, lectins and baeocystin. In order to prevent and remedy mushroom poisoning, it is significant to clarify the toxic effects and mechanisms of these bioactive substances. In this review article, we summarize the chemistry, most known toxic effects and mechanisms of major toxic substances in Inocybe mushrooms, especially muscarine, psilocybin and psilocin. Their available toxicity data (different species, different administration routes) published formerly are also summarized. In addition, the treatment and medical application of these toxic substances in Inocybe mushrooms are also discussed. We hope that this review will help understanding of the chemistry and toxicology of Inocybe mushrooms as well as the potential clinical application of its bioactive substances to benefit human beings. © 2021 by the au-thors. Licensee MDPI, Basel, Switzerland. This article is an.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of molecular sciences

ISSN

1661-6596

e-ISSN

—

Volume of the periodical

22

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

"Article number 2218"

UT code for WoS article

000623890600001

EID of the result in the Scopus database

2-s2.0-85101356269