Accurate Determination of the Orientational Distribution of a Fluorescent Molecule in a Phospholipid Membrane

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F14%3A43887349" target="_blank" >RIV/60076658:12310/14:43887349 - isvavai.cz</a>
Alternative codes found
RIV/67179843:_____/14:00427648 RIV/61388955:_____/14:00427648 RIV/61388963:_____/14:00427648
Result on the web
<a href="http://dx.doi.org/10.1021/jp4067026" target="_blank" >http://dx.doi.org/10.1021/jp4067026</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jp4067026" target="_blank" >10.1021/jp4067026</a>

Result language
angličtina
Original language name
Accurate Determination of the Orientational Distribution of a Fluorescent Molecule in a Phospholipid Membrane
Original language description
Orientation of lipophilic dye molecules within a biological membrane can report on the molecular environment, i.e., the physical and chemical properties of the surrounding membrane. This fact, however, remains under-utilized, largely because of our limited quantitative knowledge of molecular orientational distributions and the fact that robust techniques allowing experimental observation of molecular orientations of dyes in biological membranes are only being developed. In order to begin filling this lack of knowledge and to develop appropriate tools, we have investigated the membrane orientational distribution of the 3-hydroxyflavone-based membrane dye F2N12S. Results of our single- and two-photon polarization microscopy observations of linear dichroism of F2N12S-labeled giant unilamellar vesicles are consistent with a Gaussian-like orientational distribution of the transition dipole moment of the dye, with a mean tilt angle of 53.2 +/- 0.1 degrees with respect to the bilayer normal a
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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