Anti-tumour necrosis factor activity in saliva of various tick species and its appearance during the feeding period

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F17%3A43895659" target="_blank" >RIV/60076658:12310/17:43895659 - isvavai.cz</a>

Result on the web

<a href="https://folia.paru.cas.cz/pdfs/fol/2017/01/32.pdf" target="_blank" >https://folia.paru.cas.cz/pdfs/fol/2017/01/32.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14411/fp.2017.032" target="_blank" >10.14411/fp.2017.032</a>

Result language

angličtina

Original language name

Anti-tumour necrosis factor activity in saliva of various tick species and its appearance during the feeding period

Original language description

Tumour necrosis factor (TNF) plays a central role in the inflammatory process. In the skin, it contributes to immune containment of tick-transmitted pathogens like Borrelia burgdorferi. In the saliva of some tick species, active compounds are present that inhibit detection of TNF in specific ELISA. We compared the presence of anti-TNF activity in saliva or salivary gland extract from 11 tick species from the family Ixodidae and demonstrated it in genera Ixodes Latreille, 1795 and Haemaphysalis Koch, 1844. Analysis of anti-TNF activity in Ixodes ricinus (Linnaeus, 1758) saliva during the feeding period showed that it is present in the late, rapid phase of engorgement. Significance of anti-TNF activity for tick feeding and transmission of tick-borne pathogens is discussed.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30310 - Parasitology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Folia Parasitologica

ISSN

0015-5683

e-ISSN

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Volume of the periodical

64

Issue of the periodical within the volume

OCT 20 2017

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

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UT code for WoS article

000413515500001

EID of the result in the Scopus database

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