Gas aggregated Ag NPs as a matrix for small molecules: a study on natural amino acids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901341" target="_blank" >RIV/60076658:12310/20:43901341 - isvavai.cz</a>

Alternative codes found

RIV/68378271:_____/20:00538486 RIV/00216224:14310/20:00114556

Result on the web

<a href="https://link.springer.com/article/10.1007/s11051-020-05082-4" target="_blank" >https://link.springer.com/article/10.1007/s11051-020-05082-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11051-020-05082-4" target="_blank" >10.1007/s11051-020-05082-4</a>

Result language

angličtina

Original language name

Gas aggregated Ag NPs as a matrix for small molecules: a study on natural amino acids

Original language description

The use of nanomaterials as a matrix for soft ionization mass spectrometry has been investigated and reported various times. Under certain conditions, measurements of samples containing small molecules enhanced by nanomaterials have better sensitivity compared with other methods. Nanoscaled Ag prepared by various methods was reported as a substrate for surface-assisted LDI MS. Higher desorption and (in some cases) charge transfer through adduct formation with silver ion was reported. But primary ionization mechanism was through attachment of proton or alkali ion. Our approach is to overcoat the sample by Ag nanoparticles (the so-called nanoparticle-assisted LDI MS or nanoPALDI MS). As nanoparticles having adsorption maxima close to the laser wavelength, we expect an improvement in desorption enhancement, release of silver ions and (as a result of latter) increased adduct formation of [analyte+Ag](+) ions. The nanoparticles are produced by gas aggregation under low-pressure, making the process homogeneous over relatively large areas, free from impurities, and absence of capping agent often presented in colloidal nanoparticles. This work reports the detection of natural amino acids with Ag nanoparticles as a matrix. We successfully detected all amino acids (as [analyte+Ag](+) ion), including in the mixtures of few amino acids. Moreover, a formation of other adducts, particularly [analyte+Ag-3](+) and [analyte(2)+Ag](+) is reported. The differences in ion intensity ratios depending on amino acid types are discussed. The obtained results showed that laser ablation is more efficient for amino acids with hydrophobic, unique, and neutral side chains.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

21001 - Nano-materials (production and properties)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Nanoparticle Research

ISSN

1388-0764

e-ISSN

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Volume of the periodical

22

Issue of the periodical within the volume

11

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

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UT code for WoS article

000590492200001

EID of the result in the Scopus database

2-s2.0-85096213738