Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43902036" target="_blank" >RIV/60076658:12310/20:43902036 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/20:00540941
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939094/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939094/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.dib.2019.105029" target="_blank" >10.1016/j.dib.2019.105029</a>

Result language
angličtina
Original language name
Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus
Original language description
We report the proteomic datasets on the mouse macrophage cell line PMJ2R infected with tick-borne encephalitis virus (TBEV) for two and six days. Data were acquired using shotgun ultra-high resolution mass spectrometry. Peptide identifications were done using the Mascot version 2.4 (Matrix Science), and quantification was performed by a label-free approach. Protein profiles of early (two days) and late (six days) stages of infection were compared between each other and the respective control samples. Protein profiles of infected and control samples differed in the number of identified proteins and their relative abundances. Proteins detected in the TBEV-infected cells were involved in various processes related to the infection, including defense response against the virus, regulation of viral process, negative regulation of viral genome replication, RNA binding, or innate immune response. Also, proteins specific for the early and late stages of infection were identified. (C) 2019 The Author(s). Published by Elsevier Inc.
Czech name
—
Czech description
—

Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology

Project
<a href="/en/project/LTARF18021" target="_blank" >LTARF18021: Development of technologies for early detection of tick borne encephalitis, based on changes in gene expression and protein production in infected antigen-presenting cells</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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