Nuclear tRNA export in trypanosomes: a journey full of twists and turns guided by tRNA modifications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43903473" target="_blank" >RIV/60076658:12310/21:43903473 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/21:00554450
Result on the web
<a href="https://www.cambridge.org/core/journals/parasitology/article/nuclear-trna-export-in-trypanosomes-a-journey-full-of-twists-and-turns-guided-by-trna-modifications/A95F467470F56BF49C7083546F111F67" target="_blank" >https://www.cambridge.org/core/journals/parasitology/article/nuclear-trna-export-in-trypanosomes-a-journey-full-of-twists-and-turns-guided-by-trna-modifications/A95F467470F56BF49C7083546F111F67</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1017/S0031182021000482" target="_blank" >10.1017/S0031182021000482</a>

Result language
angličtina
Original language name
Nuclear tRNA export in trypanosomes: a journey full of twists and turns guided by tRNA modifications
Original language description
Transfer RNAs play a key role in protein synthesis. Following transcription, tRNAs are extensively processed prior to their departure from the nucleus to become fully functional during translation. This includes removal of 5 ' leaders and 3 ' trailers by a specific endo- and/or exonuclease, 3 ' CCA tail addition, posttranscriptional modifications and in some cases intron removal. In this minireview, the critical factors of nuclear tRNA trafficking are described based on studies in classical models such as yeast and human cell lines. In addition, recent findings and identification of novel regulatory loops of nuclear tRNA trafficking in trypanosomes are discussed with emphasis on tRNA modifications. The comparison between the representatives of opisthokonts and excavates serves here to understand the evolutionary conservation and diversity of nuclear tRNA export mechanisms.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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