Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43903966" target="_blank" >RIV/60076658:12310/21:43903966 - isvavai.cz</a>

Alternative codes found

RIV/60077344:_____/21:00551687

Result on the web

<a href="https://www.mdpi.com/1420-3049/26/19/5769" target="_blank" >https://www.mdpi.com/1420-3049/26/19/5769</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules26195769" target="_blank" >10.3390/molecules26195769</a>

Result language

angličtina

Original language name

Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review

Original language description

Secondary metabolites from marine sources have a wide range of biological activity. Marine natural products are promising candidates for lead pharmacological compounds to treat diseases that plague humans, including cancer. Cancer is a life-threatening disorder that has been difficult to overcome. It is a long-term illness that affects both young and old people. In recent years, significant attempts have been made to identify new anticancer drugs, as the existing drugs have been useless due to resistance of the malignant cells. Natural products derived from marine sources have been tested for their anticancer activity using a variety of cancer cell lines derived from humans and other sources, some of which have already been approved for clinical use, while some others are still being tested. These compounds can assault cancer cells via a variety of mechanisms, but certain cancer cells are resistant to them. As a result, the goal of this review was to look into the anticancer potential of marine natural products or their derivatives that were isolated from January 2019 to March 2020, in cancer cell lines, with a focus on the class and type of isolated compounds, source and location of isolation, cancer cell line type, and potency (IC50 values) of the isolated compounds that could be a guide for drug development.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

1420-3049

e-ISSN

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Volume of the periodical

26

Issue of the periodical within the volume

19

Country of publishing house

CH - SWITZERLAND

Number of pages

28

Pages from-to

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UT code for WoS article

000709563200001

EID of the result in the Scopus database

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