Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpio L.) spermatozoa

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F10%3A00011408" target="_blank" >RIV/60076658:12520/10:00011408 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpio L.) spermatozoa

Original language description

The effects of CBZ (a human pharmaceutical commonly present in aquatic environment) on the quality parameters and oxidative stress of common carp spermatozoa were investigated in vitro. Fish spermatozoa were incubated with different concentration of CBZ(0.2, 2.0 and 20 mg L-1) for 2 h. Results revealed that the percentage of spermatozoa motile and velocity were decreased significantly at higher concentration of CBZ (2.0 and 20 mg L-1) and a dose-dependent reduction was observed. But the viability of fish spermatozoa was not affected significantly in all CBZ treatment groups. After 2 h exposure of CBZ at higher test concentration (2.0 or 20 mg L-1), oxidative stress was apparent as reflected by the significant higher LPO and CP levels in fish spermatozoa, as well as the significant inhibition of antioxidant enzymes activities including SOD, GR and GPx. In short, CBZ can induce ROS stress in fish spermatozoa, which could impair the sperm quality and antioxidant defense system. Our resul

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GL - Fishery

OECD FORD branch

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Project

<a href="/en/project/SP%2F2E7%2F229%2F07" target="_blank" >SP/2E7/229/07: Anthropogenic pressures on the status of soils, water resources and water ecosystems in the Czech part of the international basin of the Elbe River</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemosphere

ISSN

0045-6535

e-ISSN

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Volume of the periodical

80

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

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UT code for WoS article

000279808600008

EID of the result in the Scopus database

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