Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F10%3A00011451" target="_blank" >RIV/60076658:12520/10:00011451 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Hepatic Ethoxy-, Methoxy- and Pentoxyresorufin O-Dealkylase Activities in Landrace and Duroc Pigs Stimulated with hCG
Original language description
The effect of human chorionic gonadotropin (hCG) stimulation on the activities of ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD) and pentoxyresorufin O-depentylase (PROD) was studied in intact male pigs of purebred Landrace and Duroc breeds. We found that EROD activity was suppressed by hCG-stimulation in Landrace (p = 0.004), but not Duroc pigs (p > 0.05). Generally, EROD activity was higher in Duroc pigs compared with Landrace (p = 0.017). Methoxyresorufin O-demethylase andPROD activities did not differ between groups (p > 0.05). To further characterize EROD, MROD and PROD, enzyme kinetic studies were performed. Vmax values for EROD and MROD in both breeds were lower after hCG stimuation (p < 0.001 Landrace; p < 0.05 Duroc). Additionally, Vmax values for EROD significantly differed, being higher in Duroc pigs (p < 0.05). We concluded that both hCG stimulation and breed differences may be important in the regulativ of EROD and MROD activities.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GL - Fishery
OECD FORD branch
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Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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