Bioaccumulation of psychoactive pharmaceuticals in fish in an effluent dominated stream

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F17%3A43895527" target="_blank" >RIV/60076658:12520/17:43895527 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0043135417306711" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0043135417306711</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.watres.2017.08.018" target="_blank" >10.1016/j.watres.2017.08.018</a>

Result language

angličtina

Original language name

Bioaccumulation of psychoactive pharmaceuticals in fish in an effluent dominated stream

Original language description

The treated effluent from sewage treatment plants (STP) is a major source of active pharmaceutical ingredients (APIs) that enter the aquatic environment. Bioaccumulation of 11 selected psychoactive pharmaceuticals (citalopram, clomipramine, haloperidol, hydroxyzine, levomepromazine, mianserin, mirtazapine, paroxetine, sertraline, tramadol and venlafaxine) was examined in Zivny Stream (tributary of the Blanice River, the Czech Republic), which is a small stream highly affected by effluent from the Prachatice STP. Six of the 11 pharmaceuticals were detected in grab water samples and in passive samplers. All pharmaceuticals were found in fish exposed to the stream for a defined time. The organs with highest presence of the selected pharmaceuticals were the liver and kidney; whereas only one pharmaceutical (sertraline) was detected in the brain of exposed fish. Fish plasma and muscle samples were not adequate in revealing exposure because the number of hits was much lower than that in the liver or kidney. Using the criterion of a bioaccumulation factor (BAF) &gt;= 500, citalopram, mianserin, mirtazapine and sertraline could be classified as potential bioaccumulative compounds. In combination, data from integrative passive samplers and fish liver or kidney tissue samples were complimentary in detection of target compounds and simultaneously helped to distinguish between bioconcentration and bioaccumulation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10511 - Environmental sciences (social aspects to be 5.7)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Water Research

ISSN

0043-1354

e-ISSN

—

Volume of the periodical

124

Issue of the periodical within the volume

November 2017

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

654-662

UT code for WoS article

000412251500064

EID of the result in the Scopus database

2-s2.0-85027570006