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Using fish spermatozoa in in vitro toxicity tests: A potential toxicology tool

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F21%3A43902630" target="_blank" >RIV/60076658:12520/21:43902630 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1016/j.aquaculture.2021.736647" target="_blank" >https://doi.org/10.1016/j.aquaculture.2021.736647</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.aquaculture.2021.736647" target="_blank" >10.1016/j.aquaculture.2021.736647</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Using fish spermatozoa in in vitro toxicity tests: A potential toxicology tool

  • Original language description

    In recent years, the development and implementation of new in vitro techniques for ecotoxicology and environmental risk assessment has become a priority; however, the current data indicate a lack of standardization in available in vitro sperm tests. In this review, we describe the main approaches currently used for in vitro toxicity testing of fish spermatozoa. Though fish species show huge diversity in their reproductive strategies, most are external fertilizers. Fish spermatozoa are highly specialized, transcriptionally inactive cells that become motile only upon spawning in the aqueous environment. Here, we suggest that they could become a useful toxicology tool because of their simplicity and availability. Indeed, fish spermatozoa are a promising model for genotoxicity testing, since parental exposure to genotoxicants, both in vivo and in vitro, affect embryo development. In aquaculture practice it means that evaluation of spermatozoa DNA damage could help in predicting embryo quality. Fish spermatozoa could also be useful for the study on nongenomic mechanisms of toxicity, such as the effects of xenobiotics on protein posttranslational modifications. Nevertheless, we conclude that further studies on fish spermatozoa are required to establish a clear correlation between in vitro and in vivo toxicities.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10617 - Marine biology, freshwater biology, limnology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Aquaculture

  • ISSN

    0044-8486

  • e-ISSN

  • Volume of the periodical

    539

  • Issue of the periodical within the volume

    neuveden

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000647594200008

  • EID of the result in the Scopus database

    2-s2.0-85103328129