In-feed Praziquantel treatment of grass carp (Ctenopharyngodon idella) infected with eye flukes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F24%3A43908097" target="_blank" >RIV/60076658:12520/24:43908097 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.17221/97/2023-VETMED" target="_blank" >https://doi.org/10.17221/97/2023-VETMED</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/97/2023-VETMED" target="_blank" >10.17221/97/2023-VETMED</a>

Result language

angličtina

Original language name

In-feed Praziquantel treatment of grass carp (Ctenopharyngodon idella) infected with eye flukes

Original language description

Praziquantel (PZQ) is a drug effective against several parasitic diseases of fish caused by Platyhelminthes. The study assesses the efficacy of selected in-feed PZQ doses in eliminating metacercariae Diplostomum pseudospathaceum in grass carp. The fish were infected with D. pseudospathaceum in laboratory conditions and subsequently treated with PZQ at daily doses of 30 (PZQ1), 50 (PZQ2), and 100 (PZQ3) mg/kg bw for seven days. The treatment trial was followed by a 23-day observation period during which the fish were parasitologically examined on days 0, 2, 8 and 23. Smaller fish were infected with a significantly higher (P &lt; 0.05) number of metacercariae than bigger fish among three weight groups as follows: up to 7 g &gt; 7 to 12 g &gt; 12 g. The in-feed PZQ at doses of 30, 50 and 100 mg/kg bw for seven days was 47%, 84% and 88% effective against metacercariae D. pseudospathaceum, respectively. A significant decrease (P &lt; 0.01) in moving and an increase (P &lt; 0.01) in the immotile metacercariae in the eye&apos;s lens were recorded in all the trial groups on each sampling day. An increasing proportion of motile metacercariae in the post-treatment observation period was seen in PZQ2 and PZQ3, indicating a decreasing trend in the actual efficacy in an environment with no reinfection possibility.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

<a href="/en/project/QK21010113" target="_blank" >QK21010113: Spectrum extension of medicinal products in aquaculture in the Czech Republic and evaluation of their residues in fish meat</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární medicína

ISSN

0375-8427

e-ISSN

1805-9392

Volume of the periodical

69

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

1-7

UT code for WoS article

001153313400001

EID of the result in the Scopus database

2-s2.0-85185515820