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Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F25%3A43910144" target="_blank" >RIV/60076658:12520/25:43910144 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1101/2025.04.15.25325896" target="_blank" >https://doi.org/10.1101/2025.04.15.25325896</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s44259-025-00149-5" target="_blank" >10.1038/s44259-025-00149-5</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Environmental hazards from pollution of antibiotics and resistance-driving chemicals in an urban river network from Malawi

  • Original language description

    African communities have a high prevalence of antimicrobial-resistant bacterial carriage, alongside high levels of antibiotic usage and environmental pollution. Limited access to water, sanitation and hygiene infrastructure and wastewater treatment facilities enables the dissemination of resistant bacteria, antimicrobials and antibiotic resistance-driving chemicals (ARDCs) into local rivers. Few data exist quantifying the chemical drivers of antimicrobial resistance (AMR) in urban aquatic environments from African settings. In this longitudinal surveillance study, we investigated an urban river network in Blantyre, Malawi over a continuous 12-month period, identifying a broad-range of chemical pollutants, including antibiotics, common pharmaceuticals, agricultural and industrial chemicals and heavy metals. Antimicrobial concentrations were found at levels selective for AMR and ARDCs exhibited seasonal variations, indicating that deficient sanitation infrastructure and anthropogenic factors result in high antibiotic and ARDC levels entering the river systems, which serve as an important ecological niche for the acquisition, maintenance and transmission of AMR.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>ost</sub> - Miscellaneous article in a specialist periodical

  • CEP classification

  • OECD FORD branch

    10511 - Environmental sciences (social aspects to be 5.7)

Result continuities

  • Project

    <a href="/en/project/GX20-04676X" target="_blank" >GX20-04676X: Holistic exposure and effect potential assessment of complex chemical mixtures in the aquatic environment</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    NPJ Antimicrobials and Resistance

  • ISSN

    2731-8745

  • e-ISSN

    2731-8745

  • Volume of the periodical

    3

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    14

  • Pages from-to

    nestránkováno

  • UT code for WoS article

    001636075600001

  • EID of the result in the Scopus database