Multimammate rat (Mastomys natalensis), Tristram's jird (Meriones tristrami) and Wagner's gerbil (Gerbillus dasyurus) as laboratory models of acute neosporosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F07%3A00093342" target="_blank" >RIV/60077344:_____/07:00093342 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/07:00001424
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Multimammate rat (Mastomys natalensis), Tristram's jird (Meriones tristrami) and Wagner's gerbil (Gerbillus dasyurus) as laboratory models of acute neosporosis
Original language description
To test the different sensitivity of rodents of the subfamilies Murinae and Gerbillinae, Wagner's gerbils (Gerbillus dasyurus), Tristram's jirds (Meriones tristrami) and multimammate rats (Mastomys natalensis) were inoculated with Neospora caninum tachyzoites. Clinical signs of neosporosis appeared in all inoculated animals. Histopathological examination confirmed the presence of tachyzoites in brains, lungs, skeletal muscle, myocardium, liver, in serosa of stomach and intestines, and in vesicular accessory genital glands. An examination of brains by PCR revealed presence of N. caninum DNA in all experimentally N. caninum infected rodents. The finding of N. caninum tachyzoites in the vesicular accessory genital glands of the infected gerbils suggests the usefulness of the model for demonstration of N. caninum in the male reproductive system. Moreover, the multimammate rat was a susceptible experimental immunocompetent rodent host of the subfamily Murinae.
Czech name
Krysa malá (Mastomys natalensis), pískomil Tristramův (Meriones tristrami) a pískomil Wagnerův (Gerbillus dasyurus) jako laboratorní model akutní neosporózy
Czech description
Pískomilové Gerbillus dasyurus a Meriones tristrami a krysy malé Mastomys natalensis byli infikováni tachyzoity Neospora caninum k ověření vnímavosti různých hlodavců podčeledí Murinae a Gerbillinae k infekci. Klinické příznaky neosporózy se objevily u všech inokulovaných zvířat. Histopatologické vyšetření potvrdilo přítomnost tachyzoitů v mozcích, plicích, kosterní svalovině, myokardu, játrech, na seróze žaludku a střeva, přídatných pohlavních žlázách. Vyšetření mozků pomocí PCR odhalilo N. caninum DNA. Krysy malé (Mastomys natalensis) jsou vhodným vnímavým modelem pro studium neosporózy u imunokompetentních hlodavců.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GD524%2F03%2FH133" target="_blank" >GD524/03/H133: Biology, phylogeny and ecology of parasites at organismal and molecular level</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Research in Veterinary Science
ISSN
0034-5288
e-ISSN
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Volume of the periodical
82
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
377-381
UT code for WoS article
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EID of the result in the Scopus database
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