A novel adipokinetic peptide in a water boatman (Heteroptera, Corixidae) and its bioanalogue in a saucer bug (Heteroptera, Naucoridae)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F07%3A00094796" target="_blank" >RIV/60077344:_____/07:00094796 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A novel adipokinetic peptide in a water boatman (Heteroptera, Corixidae) and its bioanalogue in a saucer bug (Heteroptera, Naucoridae)
Original language description
The corpora cardiaca (CC) of the water boatman Corixa punctato and the saucer bug Ilyocoris cimicoides, contain a substance that cause hyperlipemia in the migratory locust. The primary sequence of one octapeptide belonging to the adipokinetic hormone (AKH)/ RPCH family was deduced from the MSN electrospray mass data of CC material from each species. Whereas the saucer bug contains the known octapeptide, code-named Anaim-AKH, the water boatman has a novel peptide identified as pGlu-Leu/Ile-Asn-Phe-Ser-Pro-Ser-Trp amide, code-named Corpu-AKH. The ambiguity about the amino acid at position 2, i.e. Leu or Ile, was solved by isolating the peptide in a single-step by reversed-phase HPLC and establishing co-elution with the synthetic peptide containing Leu atposition 2. Functionally, the peptides regulate lipid mobilization, as evidenced by an adipokinetic effect after injecting synthetic Anaim-AKH and Corpu-AKH into the respective acceptor species.
Czech name
Nový adipokinetický peptid ve vodních plošticích (Heteroptera, Corixidae) and jeho bioanalog in ploštici Ilyocoris (Heteroptera, Naucoridae)
Czech description
Corpora cardiaca (CC) vodních ploštic Corixa punctato a Ilyocoris cimicoides obsahuje látky, které způsobují hyperlipemii u švába. Primární sekvence oktapeptidů náležejících do AKH/RPCH skupiny byla určena pomocí MSN elektrosprejové MS. Zatímco corpora Corixy obsahuje známý oktapeptid obsahuje Anaim-AKH, ploštice Ilyocoris má peptid identifikovaný jako pGlu-Leu/Ile-Asn-Phe-Ser-Pro-Ser-Trp amide, Corpu-AKH. Leu nebo Ile v poloze 2 byl určen izolací peptidu pomocí RP-HPLC a porovnámím koelucí se syntetickým peptidem. Oba peptidy regulují mobilizaci lipidů, prokazují pokusy se syntetickými analogy. Plavací aktivita I. Cimicoides také způsobuje hyperlipemii.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Peptides
ISSN
0196-9781
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
594-601
UT code for WoS article
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EID of the result in the Scopus database
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