Two novel tyrosine-containing peptides (Tyr4) of the adipokinetic hormone family in beetles of the families Coccinellidae and Silphidae

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00450536" target="_blank" >RIV/60077344:_____/15:00450536 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00726-015-2011-4" target="_blank" >http://link.springer.com/article/10.1007%2Fs00726-015-2011-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00726-015-2011-4" target="_blank" >10.1007/s00726-015-2011-4</a>

Result language
angličtina
Original language name
Two novel tyrosine-containing peptides (Tyr4) of the adipokinetic hormone family in beetles of the families Coccinellidae and Silphidae
Original language description
Novel members of the adipokinetic hormone family have been identified from the corpora cardiaca (CC) of two species of beetles representing two families, the Silphidae and the Coccinellidae. A crude CC of the burying beetle, Nicrophorus vespilloides wasactive in mobilizing trehalose in a heterologous assay using the cockroach Periplaneta americana, whereas the CC extract of the ladybird beetle, Harmonia axyridis, exhibited no hypertrehalosemic activity. Primary sequences were elucidated by LC-MS/MS revealing an octapeptide with an unusual tyrosine residue at position 4 for each species: pGlu-Leu-Thr-Tyr-Ser-Thr-Gly-Trp amide for N. vespilloides (code-named Nicve-AKH) and pGlu-Ile-Asn-Tyr-Ser-Thr-Gly-Trp amide for H. axyridis (code-named Harax-AKH). Moreover, synthetic peptides were shown to be active in the heterologous cockroach assay system, but Harax-AKH only at a dose of 30 pmol. It appears that the tyrosine residue at position 4 can be used as a diagnostic feature for certain bee
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—

Project
<a href="/en/project/GA13-18509S" target="_blank" >GA13-18509S: New alkyl chloroformate labeling strategies for the targeted and comparative mass spectrometry-based metabolomics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)