Novel adipokinetic hormones in the kissing bugs Rhodnius prolixus, Triatoma infestans, Dipetalogaster maxima and Panstrongylus megistrus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00384207" target="_blank" >RIV/60077344:_____/13:00384207 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0196978112004433" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0196978112004433</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.peptides.2012.09.032" target="_blank" >10.1016/j.peptides.2012.09.032</a>

Result language

angličtina

Original language name

Novel adipokinetic hormones in the kissing bugs Rhodnius prolixus, Triatoma infestans, Dipetalogaster maxima and Panstrongylus megistrus

Original language description

Peptides of the adipokinetic family (AKH) were isolated and sequenced from the retrocerebral corpora cardiaca of four kissing bugs which are all vectors of the protozoan Trypanosoma cruzi responsible for Chagas? disease. The sequence of three novel AKHswere deduced from the multiple MSN electrospray mass data: the octapeptide pGlu-Leu-Thr-Phe-Ser-Thr-Asp-Trp amide (denoted Rhopr-AKH) in Rhodnius prolixus and Panstrongylus megistus, the nonapeptide pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-Gly amide (denoted Triin-AKH) in Triatoma infestans and the decapeptide pGlu-Leu-Thr-Phe-Ser-Asp-Gly-Trp-Gly-Asn amide (denoted Dipma-AKH) in Dipetalogaster maxima. The sequences were confirmed by identical behavior of natural and synthetic forms in reversed-phase HPLC and byCID-MS mass spectra. Conspecific injections of a dose of 10 pmol of the respective synthetic peptides resulted in a small but significant increase of the lipid concentration in the hemolymph. These experiments suggest that AKHs in kissin

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

<a href="/en/project/NT11513" target="_blank" >NT11513: Profiling of neurosteroid conjugates and other acidic metabolites in body fluids and their perspective in clinical diagnostics</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Peptides

ISSN

0196-9781

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

MAR 10

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

21-30

UT code for WoS article

000320849800005

EID of the result in the Scopus database

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