Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F11%3A00359223" target="_blank" >RIV/60077344:_____/11:00359223 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.ijpara.2011.02.001" target="_blank" >http://dx.doi.org/10.1016/j.ijpara.2011.02.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijpara.2011.02.001" target="_blank" >10.1016/j.ijpara.2011.02.001</a>

Result language

angličtina

Original language name

Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission

Original language description

Insecticide-impregnated nets can kill triatomine bugs, but it remains unclear whether they can protect against Chagas disease transmission. In a field trial in Queque?a, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showed significantly lower antibody responses to saliva of Triatoma infestans compared with animals placed in pre-existing control enclosures. Our results strongly suggest that insecticide-treated nets prevent triatomine bites and can thereby protect against infection with Trypanosoma cruzi. Anti-salivary immunoassays are powerful new tools to evaluate intervention strategies against Chagas disease.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/GPP302%2F11%2FP798" target="_blank" >GPP302/11/P798: Development of recombinant salivary antigens of Triatoma infestans for the detection of low-level infestation of triatomines</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal for Parasitology

ISSN

0020-7519

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

6

Country of publishing house

AU - AUSTRALIA

Number of pages

4

Pages from-to

591-594

UT code for WoS article

000291420800001

EID of the result in the Scopus database

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