Relation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F11%3A00364901" target="_blank" >RIV/60077344:_____/11:00364901 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1099/vir.0.032417-0" target="_blank" >http://dx.doi.org/10.1099/vir.0.032417-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1099/vir.0.032417-0" target="_blank" >10.1099/vir.0.032417-0</a>

Result language

angličtina

Original language name

Relation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe

Original language description

Tick-borne encephalitis virus (TBEV) is the most important arboviral agent causing disease of the central nervous system in central Europe. In this study, 61 TBEV E gene sequences derived from 48 isolates from the Czech Republic (CR), and 4 isolates and9 TBEV strains detected in ticks from Germany (1954 to 2009), were sequenced and subjected to phylogenetic and Bayesian phylodynamic. The general Eurasian continental east-to-west pattern of the spread of TBEV was confirmed at the regional level but is interlaced with spreading that arises because of local geography and anthropogenic influence. This spread is reflected by the disease pattern in the CR that has been observed since 1991. The overall evolutionary rate was estimated to be approximately 8x10(-4) substitutions per nucleotide per year. The analysis of the TBEV E genes of 11 strains isolated at one natural focus in Zd'ar Kaplice proved for the first time that TBEV is indeed subject to local evolution.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of General Virology

ISSN

0022-1317

e-ISSN

—

Volume of the periodical

92

Issue of the periodical within the volume

—

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

1906-1916

UT code for WoS article

000293488800020

EID of the result in the Scopus database

—