Anaplasma phagocytophilum: deceptively simple or simply deceptive?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F12%3A00377654" target="_blank" >RIV/60077344:_____/12:00377654 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2217/FMB.12.45" target="_blank" >http://dx.doi.org/10.2217/FMB.12.45</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2217/FMB.12.45" target="_blank" >10.2217/FMB.12.45</a>

Result language
angličtina
Original language name
Anaplasma phagocytophilum: deceptively simple or simply deceptive?
Original language description
Anaplasma phagocytophilum is an obligate intracellular rickettsial pathogen transmitted by ixodid ticks. This bacterium colonizes myeloid and nonmyeloid cells and causes human granulocytic anaplasmosis - an important immunopathological vector-borne disease in the USA, Europe and Asia. Recent studies uncovered novel insights into the mechanisms of A. phagocytophilum pathogenesis and immunity. Here, we provide an overview of the underlying events by which the immune system responds to A. phagocytophilum infection, how this pathogen counteracts host immunity and the contribution of the tick vector for microbial transmission. We also discuss current scientific gaps in the knowledge of A. phagocytophilum biology for the purpose of exchanging research perspectives.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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