Telomeres: Their structure and maintenance

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00390569" target="_blank" >RIV/60077344:_____/13:00390569 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.5772/51356" target="_blank" >http://dx.doi.org/10.5772/51356</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5772/51356" target="_blank" >10.5772/51356</a>

Result language
angličtina
Original language name
Telomeres: Their structure and maintenance
Original language description
Telomeres are essential nucleoprotein structures at the ends of eukaryotic chromosomes. They play several essential roles preserving genome stability and function. In the absence of special telomere maintenance mechanisms telomeres shorten with every round of DNA replication. The telomere shortening leads to replicative senescence and apoptosis. Several telomere maintenance mechanisms have been identified; these are reflected in several known types of telomeres. In most eukaryotes telomeres comprise a tandem array of a short, 5-8 bp, well conserved repeat unit, and telomere length is maintained by telomerase, a specialized reverse transcriptase that carries its own RNA template and adds telomeric sequences onto chromosome ends. Nevertheless, in some organisms the array of short telomeric sequence motifs has been replaced with less conventional sequences, such as satellite sequences or transposable elements.
Czech name
—
Czech description
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Project
<a href="/en/project/GAP501%2F10%2F1215" target="_blank" >GAP501/10/1215: Stress hormones and their potential usage in insect pest control</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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