Regulation of lupulin biosynthesis by hop transcription regulation factors and some strategies to enter the regulation network

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F13%3A00426691" target="_blank" >RIV/60077344:_____/13:00426691 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Regulation of lupulin biosynthesis by hop transcription regulation factors and some strategies to enter the regulation network
Original language description
Our recent results showed the involvement of several key transcription factors from Myb (M), bHLH (B) and WDR (W) families in the regulation of chs_H1 and omt1 gene by WRKY, W1 and silencing suppressors. We have identified lupulin specific ternary Hls-M3B2W1, M2B2W1, binary Hls-M3B2; M2B2; B2W; M1W1; WRKY1W1 complexes, promoter activity modulators like HlbZip1 and 2 TFs and inhibitors like HlMyb7 that are quite selective for different promoters. Recently, to enter the network regulation of X, we initiated analysis of key TF promoters to identify secondary TFs and possible TFs autoregulation. To analyze the regulatory networks, we include viroid-induced mRNA-imbalancing pathogenesis, where target mRNAs were predicted by the bioinformatic methods.
Czech name
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Czech description
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Project
<a href="/en/project/GA13-03037S" target="_blank" >GA13-03037S: Combinatorial regulation and network of transcription factors involved in the biosynthesis of medicinal prenylflavonoids in hop (Humulus lupulus L.).</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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