Subtyping Cryptosporidium ubiquitum, a Zoonotic Pathogen Emerging in Humans

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00429417" target="_blank" >RIV/60077344:_____/14:00429417 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.3201/eid2002.121797" target="_blank" >http://dx.doi.org/10.3201/eid2002.121797</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3201/eid2002.121797" target="_blank" >10.3201/eid2002.121797</a>

Result language

angličtina

Original language name

Subtyping Cryptosporidium ubiquitum, a Zoonotic Pathogen Emerging in Humans

Original language description

Cryptosporidium ubiquitum is an emerging zoonotic pathogen. In the past, it was not possible to identify an association between cases of human and animal infection. We conducted a genomic survey of the species, developed a subtyping tool targeting the 60-kDa glycoprotein (gp60) gene, and identified 6 subtype families (XIIa-XIIf) of C. ubiquitum. Host adaptation was apparent at the gp60 locus; subtype XIIa was found in ruminants worldwide, subtype families XIIb-XIId were found in rodents in the United States, and XIIe and XIIf were found in rodents in the Slovak Republic. Humans in the United States were infected with isolates of subtypes XIIb-XIId, whereas those in other areas were infected primarily with subtype XIIa isolates. In addition, subtype families XIIb and XIId were detected in drinking source water in the United States. Contact with C. ubiquitum-infected sheep and drinking water contaminated by infected wildlife could be sources of human infections.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/LH11061" target="_blank" >LH11061: Diversity, biology and phylogeny of Cryptosporidium spp. parasiting in rodents</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Emerging Infectious Diseases

ISSN

1080-6040

e-ISSN

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Volume of the periodical

20

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

217-224

UT code for WoS article

000330553800006

EID of the result in the Scopus database

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