Identification and partial characterisation of new members of the Ixodes ricinus defensin family

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00430609" target="_blank" >RIV/60077344:_____/14:00430609 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12310/14:43887333

Result on the web

<a href="http://dx.doi.org/10.1016/j.gene.2014.03.002" target="_blank" >http://dx.doi.org/10.1016/j.gene.2014.03.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.gene.2014.03.002" target="_blank" >10.1016/j.gene.2014.03.002</a>

Result language

angličtina

Original language name

Identification and partial characterisation of new members of the Ixodes ricinus defensin family

Original language description

The hard-bodied tick Ixodes ricinus (castor bean tick) is the most common tick species in Europe.I. ricinus is a vector of the causative agents of diseases that affect humans and animals including tick-borne encephalitis, borreliosis, tick-borne fever and babesiosis. The innate immune system provides ticks with quite an efficient defence against some pathogenic microorganisms in the event of their penetration into the tick body or through the blood meal. Antimicrobial peptides (AMPs) constitute an important feature of the tick immune system. Defensins are a well-known class of AMPs. Members of the defensin family of proteins have been reported in several tick species. So far, only two defensins had been identified from I. ricinus. In this study, we report the identification of six novel putative defensins from I. ricinus at the genomic and transcriptional levels. At the genomic level they show differences with one being intronless, while others contain two introns. The expression patte

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Gene

ISSN

0378-1119

e-ISSN

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Volume of the periodical

540

Issue of the periodical within the volume

2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

146-152

UT code for WoS article

000335102200003

EID of the result in the Scopus database

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