An Updated Insight into the Sialotranscriptome of Triatoma infestans: Developmental Stage and Geographic Variations
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00439561" target="_blank" >RIV/60077344:_____/14:00439561 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pntd.0003372" target="_blank" >http://dx.doi.org/10.1371/journal.pntd.0003372</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pntd.0003372" target="_blank" >10.1371/journal.pntd.0003372</a>
Alternative languages
Result language
angličtina
Original language name
An Updated Insight into the Sialotranscriptome of Triatoma infestans: Developmental Stage and Geographic Variations
Original language description
BACKGROUND: Triatoma infestans is the main vector of Chagas disease in South America. As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. These salivary components can be immunologically recognized by their vector's hosts and targeted with antibodies that might disrupt blood feeding. These antibodies can be used to detect vector exposure using immunoassays. Antibodies may also contribute to the fast evolution of the salivary cocktail. METHODOLOGY: Salivary gland cDNA libraries from nymphal and adult T. infestans of breeding colonies originating from different locations (Argentina, Chile, Peru and Bolivia), and cDNA libraries originating from F1 populations of Bolivia, were sequenced using Illumina technology. Coding sequences (CDS) were extracted from the assembled reads, the numbers of reads mapped to these CDS, sequences were functionally annotated and p
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LH12002" target="_blank" >LH12002: Next-generation sequencing of salivary gland gene transcripts of Triatoma infestans for the discovery of triatomine exposure markers</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS Neglected Tropical Diseases
ISSN
1935-2735
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
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UT code for WoS article
000346701000045
EID of the result in the Scopus database
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