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Modulation of host immunity by tick saliva

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00453381" target="_blank" >RIV/60077344:_____/15:00453381 - isvavai.cz</a>

  • Alternative codes found

    RIV/60076658:12310/15:43890250

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.jprot.2015.07.005" target="_blank" >http://dx.doi.org/10.1016/j.jprot.2015.07.005</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jprot.2015.07.005" target="_blank" >10.1016/j.jprot.2015.07.005</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Modulation of host immunity by tick saliva

  • Original language description

    Next generation sequencing and proteomics have helped to comprehensively characterize gene expression in tick salivary glands at both the transcriptome and the proteome level. Functional data are, however, lacking. Given that tick salivary secretions arecritical to the success of the tick transmission lifecycle and, as a consequence, for host colonization by the pathogens they spread, we thoroughly review here the literature on the known interactions between tick saliva (or tick salivary gland extracts) and the innate and adaptive vertebrate immune system. The information is intended to serve as a reference for functional characterization of the numerous genes and proteins expressed in tick salivary glands with an ultimate goal to develop novel vectorand pathogen control strategies. /nSignificance: We overview all the known interactions of tick saliva with the vertebrate immune system. The provided information is important, given the recent developments in high-throughput transcripto

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP502%2F12%2F2409" target="_blank" >GAP502/12/2409: Investigating the role of tick salivary protease inhibitors at the interface between ticks, pathogens and the vertebrate host</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Proteomics

  • ISSN

    1874-3919

  • e-ISSN

  • Volume of the periodical

    128

  • Issue of the periodical within the volume

    OCT 14 2015

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    11

  • Pages from-to

    58-68

  • UT code for WoS article

    000364882200006

  • EID of the result in the Scopus database