Modulation of host immunity by tick saliva

Result code in IS VaVaI

RIV/60077344:_____/15:00453381 - isvavai.cz

Alternative codes found

RIV/60076658:12310/15:43890250

Result on the web

http://dx.doi.org/10.1016/j.jprot.2015.07.005

DOI - Digital Object Identifier

10.1016/j.jprot.2015.07.005

Result language

angličtina

Original language name

Modulation of host immunity by tick saliva

Original language description

Next generation sequencing and proteomics have helped to comprehensively characterize gene expression in tick salivary glands at both the transcriptome and the proteome level. Functional data are, however, lacking. Given that tick salivary secretions arecritical to the success of the tick transmission lifecycle and, as a consequence, for host colonization by the pathogens they spread, we thoroughly review here the literature on the known interactions between tick saliva (or tick salivary gland extracts) and the innate and adaptive vertebrate immune system. The information is intended to serve as a reference for functional characterization of the numerous genes and proteins expressed in tick salivary glands with an ultimate goal to develop novel vectorand pathogen control strategies. /nSignificance: We overview all the known interactions of tick saliva with the vertebrate immune system. The provided information is important, given the recent developments in high-throughput transcripto

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

GAP502/12/2409: Investigating the role of tick salivary protease inhibitors at the interface between ticks, pathogens and the vertebrate host

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Proteomics

ISSN

1874-3919

e-ISSN

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Volume of the periodical

128

Issue of the periodical within the volume

OCT 14 2015

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

58-68

UT code for WoS article

000364882200006

EID of the result in the Scopus database

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