Identification and bioactivity evaluation of the first neuropeptide from the lesser-known insect order Embioptera (webspinner)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F16%3A00459064" target="_blank" >RIV/60077344:_____/16:00459064 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00726-016-2229-9" target="_blank" >http://link.springer.com/article/10.1007%2Fs00726-016-2229-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00726-016-2229-9" target="_blank" >10.1007/s00726-016-2229-9</a>
Alternative languages
Result language
angličtina
Original language name
Identification and bioactivity evaluation of the first neuropeptide from the lesser-known insect order Embioptera (webspinner)
Original language description
A species of the poorly studied order Embioptera, the webspinner Oligotoma saundersii, was investigated for the peptides of the adipokinetic hormone (AKH) family. A methanolic extract of its corpora cardiaca (CC) effects carbohydrate mobilization in the cockroach, Periplaneta americana, and LC-ESI MS analysis revealed one decapeptide elucidated as pEVNFSPNWGG amide in the CC of O. saundersii. It is a novel member of the AKH family and its synthetic form has strong hypertrehalosemic activity in the American cockroach. An analog with the reversed order of the proline and asparagine residues, viz. N6 P7 -Olisa-AKH, had negligible activity thus, sheddingnlight on the requirements of the cockroach AKH receptor. The CC from an individual webspinner contains less than one pmol of Olisa-AKH. Comparison of the AKH sequences from the major orders of the Polyneoptera does not point to a close phylogenetic relationship between webspinners and stick insects.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GA13-18509S" target="_blank" >GA13-18509S: New alkyl chloroformate labeling strategies for the targeted and comparative mass spectrometry-based metabolomics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Amino Acids
ISSN
0939-4451
e-ISSN
—
Volume of the periodical
48
Issue of the periodical within the volume
7
Country of publishing house
AT - AUSTRIA
Number of pages
8
Pages from-to
1677-1684
UT code for WoS article
000377409900013
EID of the result in the Scopus database
2-s2.0-84963645414