Role of adipokinetic hormone and adenosine in the anti-stress response in Drosophila melanogaster
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F16%3A00461372" target="_blank" >RIV/60077344:_____/16:00461372 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/16:43890868
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0022191016301937" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0022191016301937</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jinsphys.2016.06.010" target="_blank" >10.1016/j.jinsphys.2016.06.010</a>
Alternative languages
Result language
angličtina
Original language name
Role of adipokinetic hormone and adenosine in the anti-stress response in Drosophila melanogaster
Original language description
The role of adipokinetic hormone (AKH) and adenosine in the anti-stress response was studied in Drosophila melanogaster larvae and adults carrying a mutation in the Akh gene (Akh1), the adenosine receptor gene (AdoR1), or in both of these genes (Akh1 AdoR1 double mutant). Stress was induced by starvation or by the addition of an oxidative stressor paraquat (PQ) to food. All oxidative stress characteristics modified by mutations in Akh gene were restored or even improved by rescue’ mutation in flies which ectopically express Akh. Thus, the results of the present study demonstrate the important roles of AKH and adenosine in the anti-stress response elicited by PQ in a D. melanogaster model, and provide the first evidence for the involvement of adenosine in the anti-oxidative stress response in insects.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA14-07172S" target="_blank" >GA14-07172S: Anti-stress reactions regulating metabolic homeostasis in insects</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Insect Physiology
ISSN
0022-1910
e-ISSN
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Volume of the periodical
91-92
Issue of the periodical within the volume
AUG 01
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
39-47
UT code for WoS article
000381532000006
EID of the result in the Scopus database
2-s2.0-84977512429