All For One and One For All on the Tick-Host Battlefield
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F16%3A00461855" target="_blank" >RIV/60077344:_____/16:00461855 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/16:43890653
Result on the web
<a href="http://dx.doi.org/10.1016/j.pt.2016.01.004" target="_blank" >http://dx.doi.org/10.1016/j.pt.2016.01.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.pt.2016.01.004" target="_blank" >10.1016/j.pt.2016.01.004</a>
Alternative languages
Result language
angličtina
Original language name
All For One and One For All on the Tick-Host Battlefield
Original language description
The saliva of ixodid ticks contains a mixture of bioactive molecules that target a wide spectrum of host defense mechanisms to allow ticks to feed on the vertebrate host for several days. Tick salivary proteins cluster in multigenic protein families, and individual family members display redundancy and pluripotency in their action to ameliorate or evade host immune responses. It is now clear that members of different protein families can target the same cellular or molecular pathway of the host physiological response to tick feeding. We present and discuss our hypothesis that redundancy and pluripotency evolved in tick salivary immunomodulators to evade immune recognition by the host while retaining the immunomodulatory potential of their saliva.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP502%2F12%2F2409" target="_blank" >GAP502/12/2409: Investigating the role of tick salivary protease inhibitors at the interface between ticks, pathogens and the vertebrate host</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Trends in Parasitology
ISSN
1471-4922
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
368-377
UT code for WoS article
000376056300006
EID of the result in the Scopus database
2-s2.0-84961848651