Tuning the mechanical properties of BIEE-crosslinked semi-interpenetrating, double-hydrophilic hydrogels
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F18%3A00491107" target="_blank" >RIV/60077344:_____/18:00491107 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/18:73588207
Result on the web
<a href="http://dx.doi.org/10.1002/mame.201700643" target="_blank" >http://dx.doi.org/10.1002/mame.201700643</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/mame.201700643" target="_blank" >10.1002/mame.201700643</a>
Alternative languages
Result language
angličtina
Original language name
Tuning the mechanical properties of BIEE-crosslinked semi-interpenetrating, double-hydrophilic hydrogels
Original language description
Double-hydrophilic, semi-interpenetrating (semi-IPN) hydrogels are synthesized by encapsulating hydrophilic polyvinylpyrrolidone (PVP) linear chains in structure-defined 1,2-bis-(2-iodoethoxy)ethane (BIEE)-crosslinked (poly(2-(dimethylamino)ethyl methacrylate) (pDMAEMA) hydrogels. A series of semi-IPN double-hydrophilic hydrogels are prepared in which the pDMAEMA/BIEE content is kept the same and only the PVP content is varied, from 0 up to 33wt%. The mechanical properties of the water-swollen hydrogels are experimentally evaluated under unconfined compressive loading conditions, while a nonlinear hyperelastic constitutive equation is used to predict their mechanical response. No significant difference is found in the mechanical response of the semi-IPN PVP/pDMAEMA/BIEE hydrogel containing 5wt% PVP compared to the pDMAEMA/BIEE analog, however, for greater loading percentages (15 and 33wt% of PVP), the semi-IPN hydrogels exhibit less stiffness/higher ductility. Furthermore, in vitro biocompatibility studies are carried out for the pDMAEMA/BIEE and the semi-IPN PVP/pDMAEMA/BIEE, indicating that both the formulations exhibit no toxicity in cultured cells.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
<a href="/en/project/LO1305" target="_blank" >LO1305: Development of the center of advanced technologies and materials</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Macromolecular Materials and Engineering
ISSN
1438-7492
e-ISSN
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Volume of the periodical
303
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
9
Pages from-to
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UT code for WoS article
000435279800004
EID of the result in the Scopus database
2-s2.0-85048573129