Message in a vesicle trans-kingdom intercommunication at the vector-host interface

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F19%3A00518848" target="_blank" >RIV/60077344:_____/19:00518848 - isvavai.cz</a>

Result on the web

<a href="https://jcs.biologists.org/content/joces/132/6/jcs224212.full.pdf" target="_blank" >https://jcs.biologists.org/content/joces/132/6/jcs224212.full.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1242/jcs.224212" target="_blank" >10.1242/jcs.224212</a>

Result language

angličtina

Original language name

Message in a vesicle trans-kingdom intercommunication at the vector-host interface

Original language description

Vector-borne diseases cause over 700,000 deaths annually and represent 17% of all infectious illnesses worldwide. This public health menace highlights the importance of understanding how arthropod vectors, microbes and their mammalian hosts interact. Currently, an emphasis of the scientific enterprise is at the vector-host interface where human pathogens are acquired and transmitted. At this spatial junction, arthropod effector molecules are secreted, enabling microbial pathogenesis and disease. Extracellular vesicles manipulate signaling networks by carrying proteins, lipids, carbohydrates and regulatory nucleic acids. Therefore, they are well positioned to aid in cell-to-cell communication and mediate molecular interactions. This Review briefly discusses exosome and microvesicle biogenesis, their cargo, and the role that nanovesicles play during pathogen spread, host colonization and disease pathogenesis. We then focus on the role of extracellular vesicles in dictating microbial pathogenesis and host immunity during transmission of vector-borne pathogens.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10601 - Cell biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Cell Science

ISSN

1477-9137

e-ISSN

—

Volume of the periodical

132

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

jcs224212

UT code for WoS article

000462864300011

EID of the result in the Scopus database

2-s2.0-85063290362