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Evolution and diversification of the nuclear envelope

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F21%3A00554438" target="_blank" >RIV/60077344:_____/21:00554438 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.tandfonline.com/doi/full/10.1080/19491034.2021.1874135" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/19491034.2021.1874135</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/19491034.2021.1874135" target="_blank" >10.1080/19491034.2021.1874135</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evolution and diversification of the nuclear envelope

  • Original language description

    Eukaryotic cells arose similar to 1.5 billion years ago, with the endomembrane system a central feature, facilitating evolution of intracellular compartments. Endomembranes include the nuclear envelope (NE) dividing the cytoplasm and nucleoplasm. The NE possesses universal features: a double lipid bilayer membrane, nuclear pore complexes (NPCs), and continuity with the endoplasmic reticulum, indicating common evolutionary origin. However, levels of specialization between lineages remains unclear, despite distinct mechanisms underpinning various nuclear activities. Several distinct modes of molecular evolution facilitate organellar diversification and to understand which apply to the NE, we exploited proteomic datasets of purified nuclear envelopes from model systems for comparative analysis. We find enrichment of core nuclear functions amongst the widely conserved proteins to be less numerous than lineage-specific cohorts, but enriched in core nuclear functions. This, together with consideration of additional evidence, suggests that, despite a common origin, the NE has evolved as a highly diverse organelle with significant lineage-specific functionality.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nucleus

  • ISSN

    1949-1034

  • e-ISSN

    1949-1042

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    22

  • Pages from-to

    21-41

  • UT code for WoS article

    000616529900001

  • EID of the result in the Scopus database

    2-s2.0-85100568735