Insect cross-tolerance to freezing and drought stress: role of metabolic rearrangement
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00558034" target="_blank" >RIV/60077344:_____/22:00558034 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/22:43904721
Result on the web
<a href="https://royalsocietypublishing.org/doi/10.1098/rspb.2022.0308" target="_blank" >https://royalsocietypublishing.org/doi/10.1098/rspb.2022.0308</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1098/rspb.2022.0308" target="_blank" >10.1098/rspb.2022.0308</a>
Alternative languages
Result language
angličtina
Original language name
Insect cross-tolerance to freezing and drought stress: role of metabolic rearrangement
Original language description
The accumulation of trehalose has been suggested as a mechanism underlying insect cross-tolerance to cold/freezing and drought. Here we show that exposing diapausing larvae of the drosophilid fly, Chymomyza costata to dry conditions significantly stimulates their freeze tolerance. It does not, however, improve their tolerance to desiccation, nor does it significantly affect trehalose concentrations. Next, we use metabolomics to compare the complex alterations to intermediary metabolism pathways in response to three environmental factors with different ecological meanings: environmental drought (an environmental stressor causing mortality), decreasing ambient temperatures (an acclimation stimulus for improvement of cold hardiness), and short days (an environmental signal inducing diapause). We show that all three factors trigger qualitatively similar metabolic rearrangement and a similar phenotypic outcome - improved larval freeze tolerance. The similarities in metabolic response include (but are not restricted to) the accumulation of typical compatible solutes and the accumulation of energy-rich molecules (phosphagens). Based on these results, we suggest that transition to metabolic suppression (a state in which chemical energy demand is relatively low but need for stabilization of macromolecules is high) represents a common axis of metabolic pathway reorganization towards accumulation of non-toxic cytoprotective compounds, which in turn stimulates larval freeze tolerance.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
<a href="/en/project/GA19-13381S" target="_blank" >GA19-13381S: Cryoprotectants and cryoprotection: assessment of candidate molecules derived from research on freeze-tolerant drosophilid fly.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the Royal Society B-Biological Sciences
ISSN
0962-8452
e-ISSN
1471-2954
Volume of the periodical
289
Issue of the periodical within the volume
JUN 8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
20220308
UT code for WoS article
000807984900013
EID of the result in the Scopus database
2-s2.0-85131475074