Molecular Mechanism of the Circadian Clock
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00571397" target="_blank" >RIV/60077344:_____/23:00571397 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/chapter/10.1007/978-981-99-0726-7_4" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-99-0726-7_4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-981-99-0726-7_4" target="_blank" >10.1007/978-981-99-0726-7_4</a>
Alternative languages
Result language
angličtina
Original language name
Molecular Mechanism of the Circadian Clock
Original language description
Nearly all organisms possess a circadian clock, a genetically determined device that generates endogenous oscillations with a period of approximately 24 h. From a molecular perspective, the circadian clock relies on negative transcription-translation feedback loops. In insects, the molecular and genetic basis of the circadian clock machinery has been revealed by the remarkable genetic tools available to the fruit fly Drosophila melanogaster. However, the dawn of reverse genetics methods applicable to nonmodel species has led to recent significant advances in our understanding of the circadian clock beyond Drosophila. To illustrate the molecular mechanism behind the insect circadian clock, the first section focuses primarily on Drosophila melanogaster as the best established and most detailed insect model. Conserved components of the insect clocks are then identified at the genetic level, and lineage-specific idiosyncrasies and variations in setup are highlighted and further discussed. Functional evidence from non-Drosophila insects is reviewed, and the main descriptive data from molecular biology are presented in an evolutionary context and briefly summarized.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
10605 - Developmental biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Insect Chronobiology
ISBN
978-981-99-0725-0
Number of pages of the result
36
Pages from-to
49-84
Number of pages of the book
357
Publisher name
Springer
Place of publication
Singapore
UT code for WoS chapter
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