The role of repetitive sequences in repatterning of major ribosomal DNA clusters in Lepidoptera
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00572837" target="_blank" >RIV/60077344:_____/23:00572837 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/23:43906472
Result on the web
<a href="https://academic.oup.com/gbe/article-pdf/15/6/evad090/50569543/evad090.pdf" target="_blank" >https://academic.oup.com/gbe/article-pdf/15/6/evad090/50569543/evad090.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/gbe/evad090" target="_blank" >10.1093/gbe/evad090</a>
Alternative languages
Result language
angličtina
Original language name
The role of repetitive sequences in repatterning of major ribosomal DNA clusters in Lepidoptera
Original language description
Genes for major ribosomal RNAs (rDNA) are present in multiple copies mainly organized in tandem arrays. The number and position of rDNA loci can change dynamically and their repatterning is presumably driven by other repetitive sequences. We explored a peculiar rDNA organization in several representatives of Lepidoptera with either extremely large or numerous rDNA clusters. We combined molecular cytogenetics with analyses of second- and third-generation sequencing data to show that rDNA spreads as a transcription unit and reveal association between rDNA and various repeats. Furthermore, we performed comparative long read analyses among the species with derived rDNA distribution and moths with a single rDNA locus, which is considered ancestral. Our results suggest that satellite arrays, rather than mobile elements, facilitate homology-mediated spread of rDNA via either integration of extrachromosomal rDNA circles or ectopic recombination. The latter arguably better explains preferential spread of rDNA into terminal regions of lepidopteran chromosomes as efficiency of ectopic recombination depends on the proximity of homologous sequences to telomeres.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Genome Biology and Evolution
ISSN
1759-6653
e-ISSN
1759-6653
Volume of the periodical
15
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
17
Pages from-to
evad090
UT code for WoS article
001004108900001
EID of the result in the Scopus database
2-s2.0-85162992285