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Comparison of Heavy Metal Distribution in Mouse Soft Tissue Samples Prepared for Serial Block Face SEM Using Different Protocols.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00580709" target="_blank" >RIV/60077344:_____/23:00580709 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081731:_____/23:00580709

  • Result on the web

    <a href="https://academic.oup.com/mam/article/29/Supplement_1/1183/7228840?login=true" target="_blank" >https://academic.oup.com/mam/article/29/Supplement_1/1183/7228840?login=true</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comparison of Heavy Metal Distribution in Mouse Soft Tissue Samples Prepared for Serial Block Face SEM Using Different Protocols.

  • Original language description

    Serial block-face scanning electron microscopy (SBEM) is a convenient method for studying the 3D structure of larger biological samples with a volume up to mm3. Ultrathin sections are cut off the specimen using an ultramicrotome placed directly inside the SEM chamber. Back-scattered electron imaging visualises the area of interest on the newly revealed sample surface. The biggest challenges we face in SBEM are sample preparation, finding the region of interest (ROI) within the sample, sample charging during the imaging, and finally, data processing and storage. Insufficient image contrast and charging often limit visualisation and make sample preparation one of the crucial steps in the SBEM analysis.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů