Silver-enriched microdomain patterns as advanced bactericidal coatings for polymer-based medical devices

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00587480" target="_blank" >RIV/60077344:_____/24:00587480 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/24:00587480 RIV/60461373:22310/24:43929395 RIV/60461373:22330/24:43929395
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0927776524003266?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927776524003266?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.colsurfb.2024.114067" target="_blank" >10.1016/j.colsurfb.2024.114067</a>

Result language
angličtina
Original language name
Silver-enriched microdomain patterns as advanced bactericidal coatings for polymer-based medical devices
Original language description
Today, it would be difficult for us to live a full life without polymers, especially in medicine, where its applicability is constantly expanding, giving satisfactory results without any harm effects on health. This study focused on the formation of hexagonal domains doped with AgNPs using a KrF excimer laser (λ=248 nm) on the polyetheretherketone (PEEK) surface that acts as an unfailing source of the antibacterial agent - silver. The hexagonal structure was formed with a grid placed in front of the incident laser beam. Surfaces with immobilized silver nanoparticles (AgNPs) were observed by AFM and SEM. Changes in surface chemistry were studied by XPS. To determine the concentration of released Ag+ ions, ICP-MS analysis was used. The antibacterial tests proved the antibacterial efficacy of Ag-doped PEEK composites against Escherichia coli and Staphylococcus aureus as the most common pathogens. Because AgNPs are also known for their strong toxicity, we also included cytotoxicity tests in this study. The findings presented here contribute to the advancement of materials design in the biomedical field, offering a novel starting point for combating bacterial infections through the innovative integration of AgNPs into inert synthetic polymers.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20501 - Materials engineering

Project
<a href="/en/project/GA22-17346S" target="_blank" >GA22-17346S: Preparation and properties of nanoporous membranes with functionalized nanoparticles</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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