Reconstructing the last common ancestor of all eukaryotes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00602571" target="_blank" >RIV/60077344:_____/24:00602571 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/24:10494252
Result on the web
<a href="https://doi.org/10.1371/journal.pbio.3002917" target="_blank" >https://doi.org/10.1371/journal.pbio.3002917</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pbio.3002917" target="_blank" >10.1371/journal.pbio.3002917</a>
Alternative languages
Result language
angličtina
Original language name
Reconstructing the last common ancestor of all eukaryotes
Original language description
Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the gene repertoire of the last eukaryotic common ancestor (LECA). As data sets grow, sketching an accurate genomics-informed picture of early eukaryotic cellular complexity requires provision of analytical resources and a commitment to data sharing. Here, we summarise progress towards understanding the biology of LECA and outline a community approach to inferring its wider gene repertoire. Once assembled, a robust LECA gene set will be a useful tool for evaluating alternative hypotheses about the origin of eukaryotes and understanding the evolution of traits in all descendant lineages, with relevance in diverse fields such as cell biology, microbial ecology, biotechnology, agriculture, and medicine. In this Consensus View, we put forth the status quo and an agreed path forward to reconstruct LECA's gene content.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLOS Biology
ISSN
1544-9173
e-ISSN
1545-7885
Volume of the periodical
22
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
24
Pages from-to
e3002917
UT code for WoS article
001362522700002
EID of the result in the Scopus database
2-s2.0-85210733849