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Analysis of proteomes released from in vitro cultured eight Clostridium difficile PCR ribotypes revealed specific expression in PCR ribotypes 027 and 176 confirming their genetic relatedness and clinical importance at the proteomic level.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG33__%2F17%3AN0000002" target="_blank" >RIV/60162694:G33__/17:N0000002 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/17:00478190 RIV/00216208:11130/17:10373768 RIV/60162694:G44__/17:43889125 RIV/00064203:_____/17:10373768

  • Result on the web

    <a href="https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-017-0194-9" target="_blank" >https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-017-0194-9</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s13099-017-0194-9" target="_blank" >10.1186/s13099-017-0194-9</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Analysis of proteomes released from in vitro cultured eight Clostridium difficile PCR ribotypes revealed specific expression in PCR ribotypes 027 and 176 confirming their genetic relatedness and clinical importance at the proteomic level.

  • Original language description

    Clostridium difficile is the causative agent of C. difficile infection (CDI) that could be manifested by diarrhea, pseudomembranous colitis or life-threatening toxic megacolon. The spread of certain strains represents a significant economic burden for health-care. The epidemic successful strains are also associated with severe clinical features of CDI. Therefore, a proteomic study has been conducted that comprises proteomes released from in vitro cultured panel of eight different PCR ribotypes (RTs) and employs the combination of shotgun proteomics and label-free quantification (LFQ) approach.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Gut Pathogens

  • ISSN

    1757-4749

  • e-ISSN

    1757-4749

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    45

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    nestrankovano

  • UT code for WoS article

    000407586000001

  • EID of the result in the Scopus database