Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG38__%2F04%3A00001116" target="_blank" >RIV/60162694:G38__/04:00001116 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/04:00000027 RIV/68378041:_____/04:00100980
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA
Original language description
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD, XPG,XPC, XRCC1 and XRCC3, and the levels of chromosomalaberrations and DNA breaks in peripheral lymphocytes in a central European population.We also measured the irradiation-specific DNA repairrates and the repair rates of 8-oxoguanines in these individuals.Our results from this study suggest that markers of genotoxicity are associated with polymorphisms in genes encodingDNA repair enzymes.
Czech name
Genetický polymorfismus v genech pro reparaci DNA a jeho možné vztahy k rychlosti reparace, chromosomálním aberacím a jednořetězcovým zlomům DNA
Czech description
Genetický polymorfismus v genech pro reparaci DNA a jeho možné vztahy k rychlosti reparace, chromosomálním aberacím a jednořetězcovým zlomům DNA

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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