Proteomic analysis of antibody response in a case of laboratory-acquired infection with Francisella tularensis subsp. tularensis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F07%3A00001729" target="_blank" >RIV/60162694:G44__/07:00001729 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Proteomic analysis of antibody response in a case of laboratory-acquired infection with Francisella tularensis subsp. tularensis
Original language description
Immunoproteomic analysis was applied to study the immunoreactivity of serum samples collected at different time points from a laboratory assistant accidentally infected with highly virulent strain of Francisella tularensis subsp. tularensis. Immunoblotting showed that the spectrum of F. tularensis antigens recognized specifically by immune sera remained with the exception for 1 antigen stable for up to 16 years after infection. Using immunoproteomics approach 10 immunoreactive antigens were successfullyidentified. Several new immunogenic F. tularensis proteins were described for the first time.
Czech name
Proteomová analýza protilátkové odpovědi u laboratorního pracovníka infikovaného subtypem Francisella tularensis subsp. tularensis
Czech description
Imunoproteomová analýza byla použita ke studiu protilátkové specifity ve vzorcích séra získaných od laboratorních pracovníků náhodně infikovaných plně virulentním kmenem Francisella tularensis subsp. tularensis. Analýza vedla k identifikaci 10 různých imunoreaktivních antigenů, z nichž některé byly prokázány poprvé.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/OPUOFVZ200601" target="_blank" >OPUOFVZ200601: Crisis management after the use of biological agents</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Folia microbiologica
ISSN
0015-5632
e-ISSN
—
Volume of the periodical
52
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
194-198
UT code for WoS article
—
EID of the result in the Scopus database
—