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A comparison of the efficacy of newly developed oximes (K074, K075) and commonly used oximes (obidoxime, HI-6) to counteract tabun-induced neurotoxicity in rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F07%3A00001738" target="_blank" >RIV/60162694:G44__/07:00001738 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A comparison of the efficacy of newly developed oximes (K074, K075) and commonly used oximes (obidoxime, HI-6) to counteract tabun-induced neurotoxicity in rats

  • Original language description

    Due to their neuroprotective effects, both newly developed oximes (especially K075) appear to be more suitable oximes for the antidotal treatment of acute tabun poisonings than the oxime HI-6.

  • Czech name

    Srovnání schopnosti nově vyvinutých oximů (K074, K075) a běžně používaných oximů (obidoxim, HI-6) eliminovat tabunem vyvolané projevy neurotoxicity u potkanů

  • Czech description

    Díky svému neuroprotektivnímu účinku jsou oba nově vyvinuté oximy (zvláště K075) vhodnějšími oximy pro antidotní terapii akutních otrav tabunem než oxim HI-6.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Toxicology

  • ISSN

    0300-483X

  • e-ISSN

  • Volume of the periodical

    229

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    136-144

  • UT code for WoS article

  • EID of the result in the Scopus database